Most funds were lucky if got a board seat and control was pretty much out of the question. GPs, armed with much larger funds and access to substantial leverage, are going against deep-pocketed corporations with both sides scoring points. Theoretically speaking, corporates - able to pay higher prices for assets based on their longer term view and ability to create synergies with existing businesses - are ideal buyers for private equity portfolio companies. Armed with substantial war chests raised for the US markets, a number of private equity firms were able to capitalize on the opportunity and buy distressed assets available at fire sale prices. This volume is divided into three sections.
This includes tracking of dendritic cells in vivo, monitoring arterial smooth muscle-specific T cells in the inflamed vasculature, imaging of molecular migrations in immune synapses, and visualization of various immune cells in intact lymphoid tissues by two photon confocal imaging. Armed with substantial war chests raised for the US markets, a number of private equity firms were able to capitalize on the opportunity and buy distressed assets available at fire sale prices. Tech companies with their ultra high valuations were able to acquire traditional companies with very little more than a promise of future returns. As the numbers show, the business model did not work well and profitable deals were few and far in between. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III. This volume is divided into three sections. Theoretically speaking, corporates - able to pay higher prices for assets based on their longer term view and ability to create synergies with existing businesses - are ideal buyers for private equity portfolio companies. Most funds were lucky if got a board seat and control was pretty much out of the question. These deals were sourced through GPs' personal relationships with controlling shareholders. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. However, with secondary buyout transactions on the rise see page 9 , corporations and PE firms have found themselves engaged in fierce competition for the same deals. Then came the tech boom in , when deals were a bit topsy turvy and the "new economy" looked poised to absorb the old one. This volume highlights the current concepts of lymphocyte development, factors regulating lymphocyte trafficking and development, and specialized characteristics and functional properties of naive and memory subsets. This volume should be of interest to immunologists, molecular biologists, microbiologists, pathologists, academic physicians, cell biologists, and scientists and clinicians interested in vaccine development. The dynamics have since become a bit more balanced: Due to problems at home, many corporations chose to sit it out and as a result private equity had its pick of the best deals, and delivered handsome returns. GPs, armed with much larger funds and access to substantial leverage, are going against deep-pocketed corporations with both sides scoring points. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. When the Asian financial crisis came in , it signaled a shift in power and private equity firms, especially the larger global players, were now in the driver's seat. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. Although the relationship between Asian corporates and private equity dates back many years, it probably started blooming in the mids before the Asian financial crisis, when pioneering private equity firms fed on "corporate crumbs," i. Needless to say, private equity was not very competitive then, although with hindsight, rightfully so.
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